Search on: I DNAS, SATELLITE 
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Descriptor English:   DNA, Satellite 
Descriptor Spanish:   ADN Satélite 
Descriptor Portuguese:   DNA Satélite 
Synonyms English:   Satellite I DNA
DNA, Satellite I
DNAs, Satellite
DNAs, Satellite I
I DNA, Satellite
I DNAs, Satellite
Satellite DNAs
Satellite I DNAs
Satellite DNA  
Tree Number:   D13.444.308.480
G02.111.570.080.708.800.150
G05.360.080.708.800.150
G05.360.340.024.220.150
G05.360.340.024.850.150
Definition English:   Highly repetitive DNA sequences found in HETEROCHROMATIN, mainly near centromeres. They are composed of simple sequences (very short) (see MINISATELLITE REPEATS) repeated in tandem many times to form large blocks of sequence. Additionally, following the accumulation of mutations, these blocks of repeats have been repeated in tandem themselves. The degree of repetition is on the order of 1000 to 10 million at each locus. Loci are few, usually one or two per chromosome. They were called satellites since in density gradients, they often sediment as distinct, satellite bands separate from the bulk of genomic DNA owing to a distinct BASE COMPOSITION. 
See Related English:   Centromere
 
History Note English:   80(75); was see under DNA 1975-79 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   22160 
Unique Identifier:   D004276 

Occurrence in VHL:
 

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